INDIVIDUALITY AND THE GENOME

A COLONY OF GENETICALLY IDENTICAL E. COLI IS ACTUALLY A MOB OF ‘INDIVIDUALS’. 

UNDERSTANDING INDIVIDUALITY : 

Dr. Michael Elowitz, Physicist at California Institute of Technology has conducted experiments on colonies of genetically identical (CLONES) E. coli bacteria under identical experimental conditions and has discovered that the clones behave in different ways which could be viewed as an expression of ‘individuality’. E. coli bacteria in billions populate our intestines. Typical E. coli bacillus has about 4,000 genes. Human cells have about 20,000 genes. The bacteria have fingerprints of their own and even when they share the exact same genome, they could still be identified as ‘individuals’. Humans differ from one another in too many different ways and it is hard to count. The current human population of over six billion could be identified as the same number of individuals. Each human being has an unique genome of his own. There are millions of typographical differences between one genome and another human genome. Even identical twins are not truly identical at all as identical genes in our cells can behave differently. 

Living entities are not like simple machines. When we use a gene to make a protein, the gene may not produce a smoothly increasing supply of that protein. The gene tends to work in fits and starts and spurts out the protein. Identical genes can behave differently as the gene makes protein or remains silent depending upon the ‘Methyl’ groups that cap the DNA strands and function as ‘transducers’. These ‘Methyl’ groups sometimes fall off of DNA or become attached to new spots. Hence genetically identical individuals can have different physical identities in the natural world. The protein molecules that make up living entities, turn them into individuals. 

THE IRRELEVANCE OF EVOLUTION : 

In the natural world, all living entities exist as individuals and express their individuality. The Theory of Evolution proposes that a species can descend or arrive to become a new species by changing its genome in a gradual and incremental manner using a mechanism that is described as ‘ natural selection ‘. The mechanism of natural selection operates via a process of RANDOM and UNGUIDED mutations in the genetic code that changes the genome and eventually produces the ‘biodiversity’ that we witness in the natural world. This Theory of Evolution has no relevance to the ultimate identity of each individual member of a given species. This identity is dictated by the interplay between quantum mechanics, interactions, and disorder that generates individual variations. With the same genomes or different genomes, the living entities can only exist as individuals and they have no other choice. The evolutionary connections are not relevant to this identity. To understand the phenomenon of BIODIVERSITY, we will be forced to look at each individual member of each given species. 

THE LAW OF INDIVIDUALITY : 

Just like the Law of Conservation of Energy, I suggest that the Law of Individuality governs all the living entities and is manifested in various biological phenomena. The genes and the genetic code function in accordance with the Law of Individuality. I would describe Individuality as a Trade Mark. It is the characteristic of a biological entity. Genes and the genetic codes are the tools that an organism uses to express its Individuality. Each organism assembles its own kind of protein molecules to define its identity and to defend its existence in the natural world. 

Dr. R. Rudra Narasimham,

Kurnool Medical College, Kurnool, India.,

M.B.B.S., Class of April, 1970.

Published by WholeDude

I seek harmony between doctrines of Idealism and Realism to account for human existence. I welcome thoughts from all directions to understand the nature of Human Identity and Individuality. The multicellular human organism exists as Physical, Mental, Social, Moral, Spiritual being with a Creative Form that cannot be duplicated. For purposes of brevity and simplicity, I divide the human being into two categories; 1. The first is 'SELF' and it represents man as Physical, Mental, and Social Being and 2. The second is, the 'KNOWING-SELF' which represents man as Moral, Rational and Spiritual Being."I am Consciousness, therefore I am", is the proposition that I use to understand the nature of man's Identity and Individuality. Man is a Mortal Being whose Life and Death are operated by Oxidation-Reduction Chemical Reactions. The Physical Being is dissolved by the powerful influence of Time which seem to operate Natural Law of Aging. Things in Nature change with Time but the Identity and Individuality of Man remains the same during his Life Journey. The genotype remains unchanged while the phenotype appears to be changing all the time. In the multicellular human organism, the Consciousness functions to establish Identity of the organism and to defend its Individuality. Consciousness also establishes the Connection, Partnership, Relationship, Yoking, Joining, and Association between the energy dependent man and his energy provider. Man exists in Nature because of his ability to acquire energy from external environmental source. Consciousness in its essence refers to this awareness of energy dependence. I describe the Connection between energy seeker and energy provider as 'God Connection'. Man during all the stages of his existence, and under any given circumstance, either in good health, or ill-health exists on the basis of this 'God Connection' which is an attribute of biological or living function called Consciousness. This conditioned nature of human existence is supported by Power/Energy/Force which can be experienced as Compassion/Mercy/Grace of the Creator who created man as an Individual with unique genome that has never existed in the past and also will never exist in the future. I seek the Unity of Man in Body, Mind, and Soul unlike other common Indian traditions that seek to verify Identity between Human Soul and Divine Soul. My doctrine can be described as Unity Theory of Non-Dualism.

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2 Comments

  1. I am very glad to read the contents of this message. The notion of an individual conscious living being is one the most important mysteries in the creation. Whether it is a human being or a cell it excites one’s admiration. Does this individuality suggest any hitherto unknown ‘force’ that operates on the material componets of the individual?

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    1. Thanks for your remarks. Yes indeed, there are two other Fundamental Forces that operate in the universe and they specifically influence all living entities. I have described ‘Krupa’ and ‘Maya’ as Fundamental Forces. I would be happy to share those two pages with you.

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